Cisco AnyConnect vs Tailscale

Side-by-side from the Top 11 ranking of The 11 Best Business VPNs. Last verified June 9, 2026.

The short answer

Cisco AnyConnect ranks higher on Top 11 (#7 vs #11) for IT teams securing remote access. A legacy enterprise VPN standard, best for companies already using Cisco hardware.

At a glance

Cisco AnyConnectTailscale
Top 11 rank#7 / The 11 Best Business VPNs#11 / The 11 Best Business VPNs
Score (out of 9.4)7.97.1
Best forThe enterprise standard for Cisco shopsEffortless peer-to-peer mesh networking
Pricing$$$ (Quote-based, requires hardware)$$ ($6 to $18/user/mo)
HQSan Jose, USAToronto, Canada
Founded19842019

Cisco AnyConnect

A legacy enterprise VPN standard, best for companies already using Cisco hardware.

www.cisco.com/c/en/us/products/security/anyconnect-secure-mobility-client/index.html

See full entry in The 11 Best Business VPNs

Tailscale

A developer-focused mesh network that makes secure device-to-device connections incredibly simple.

tailscale.com/

See full entry in The 11 Best Business VPNs

Methodology and scoring weights live at /methodology. No vendor pays for placement — see about.