Cisco Secure Email Threat Defense vs Trend Micro Email and Collaboration Security

Side-by-side from the Top 11 ranking of Top 11 Email Security Software. Last verified July 4, 2026.

The short answer

Cisco Secure Email Threat Defense ranks higher on Top 11 (#6 vs #7) for IT and security leaders. Talos-backed detection wired into the Cisco stack.

At a glance

Cisco Secure Email Threat DefenseTrend Micro Email and Collaboration Security
Top 11 rank#6 / Top 11 Email Security Software#7 / Top 11 Email Security Software
Score (out of 9.4)8.58.4
Best forBest for existing Cisco security shopsBest for email plus collaboration apps
Pricing$$$ (custom, per-user enterprise pricing)$$ (roughly $3 to $6 per user per month)
HQSan Jose, USATokyo, Japan
Founded19841988

Cisco Secure Email Threat Defense

Talos-backed detection wired into the Cisco stack.

www.cisco.com/site/us/en/products/security/secure-email/index.html

See full entry in Top 11 Email Security Software

Trend Micro Email and Collaboration Security

API protection across email and collaboration apps.

www.trendmicro.com/en_us/business/products/user-protection/sps/email-and-collaboration.html

See full entry in Top 11 Email Security Software

Methodology and scoring weights live at /methodology. No vendor pays for placement — see about.