Five9 vs NICE CXone
Side-by-side from the Top 11 ranking of The 11 Best Call Center Software Platforms. Last verified June 15, 2026.
The short answer
Five9 ranks higher on Top 11 (#1 vs #3) for Support and sales teams running inbound or outbound call centers. A top-tier, reliable platform with powerful AI tools for large-scale call centers.
At a glance
| Five9 | NICE CXone | |
|---|---|---|
| Top 11 rank | #1 / The 11 Best Call Center Software Platforms | #3 / The 11 Best Call Center Software Platforms |
| Score (out of 9.4) | 9.3 | 8.9 |
| Best for | Enterprise AI & reliability | Unified enterprise CX platform |
| Pricing | $$$$ ($149 to $229+/mo) | $$$$ (Quote-based) |
| HQ | San Ramon, USA | Hoboken, USA |
| Founded | 2001 | 1986 |
Five9
A top-tier, reliable platform with powerful AI tools for large-scale call centers.
www.five9.comSee full entry in The 11 Best Call Center Software Platforms
NICE CXone
A complete suite for managing customer interactions and agent performance.
www.nice.com/products/cxoneSee full entry in The 11 Best Call Center Software Platforms
Methodology and scoring weights live at /methodology. No vendor pays for placement — see about.