Five9 vs Zendesk Talk

Side-by-side from the Top 11 ranking of The 11 Best Call Center Software Platforms. Last verified June 15, 2026.

The short answer

Five9 ranks higher on Top 11 (#1 vs #9) for Support and sales teams running inbound or outbound call centers. A top-tier, reliable platform with powerful AI tools for large-scale call centers.

At a glance

Five9Zendesk Talk
Top 11 rank#1 / The 11 Best Call Center Software Platforms#9 / The 11 Best Call Center Software Platforms
Score (out of 9.4)9.37.6
Best forEnterprise AI & reliabilityTeams using Zendesk Suite
Pricing$$$$ ($149 to $229+/mo)$$$ ($69 to $149+/mo)
HQSan Ramon, USASan Francisco, USA
Founded20012007

Five9

A top-tier, reliable platform with powerful AI tools for large-scale call centers.

www.five9.com

See full entry in The 11 Best Call Center Software Platforms

Zendesk Talk

The best and most seamless voice option for Zendesk users.

www.zendesk.com/talk

See full entry in The 11 Best Call Center Software Platforms

Methodology and scoring weights live at /methodology. No vendor pays for placement — see about.