Microsoft AutoGen vs Haystack by deepset

Side-by-side from the Top 11 ranking of The 11 Best AI Agent Builders. Last verified May 31, 2026.

The short answer

Microsoft AutoGen ranks higher on Top 11 (#4 vs #6) for Developers building autonomous AI agents and workflows. A powerful, research-backed framework for building agents that collaborate via conversation.

At a glance

Microsoft AutoGenHaystack by deepset
Top 11 rank#4 / The 11 Best AI Agent Builders#6 / The 11 Best AI Agent Builders
Score (out of 9.4)8.78.2
Best forConversational multi-agent systemsEnterprise-grade RAG & search agents
PricingFree (Open Source)Free (Open Source) + Enterprise Edition
HQRedmond, USABerlin, Germany
Founded20232018

Microsoft AutoGen

A powerful, research-backed framework for building agents that collaborate via conversation.

microsoft.github.io/autogen/

See full entry in The 11 Best AI Agent Builders

Haystack by deepset

A robust, pipeline-centric framework for building scalable enterprise RAG agents.

haystack.deepset.ai/

See full entry in The 11 Best AI Agent Builders

Methodology and scoring weights live at /methodology. No vendor pays for placement — see about.