Microsoft AutoGen vs MemGPT

Side-by-side from the Top 11 ranking of The 11 Best AI Agent Builders. Last verified May 31, 2026.

The short answer

Microsoft AutoGen ranks higher on Top 11 (#4 vs #11) for Developers building autonomous AI agents and workflows. A powerful, research-backed framework for building agents that collaborate via conversation.

At a glance

Microsoft AutoGenMemGPT
Top 11 rank#4 / The 11 Best AI Agent Builders#11 / The 11 Best AI Agent Builders
Score (out of 9.4)8.77.1
Best forConversational multi-agent systemsAgents with persistent, long-term memory
PricingFree (Open Source)Free (Open Source)
HQRedmond, USABerkeley, USA
Founded20232023

Microsoft AutoGen

A powerful, research-backed framework for building agents that collaborate via conversation.

microsoft.github.io/autogen/

See full entry in The 11 Best AI Agent Builders

MemGPT

A novel technique for giving agents persistent, long-term memory beyond context windows.

memgpt.ai/

See full entry in The 11 Best AI Agent Builders

Methodology and scoring weights live at /methodology. No vendor pays for placement — see about.