Dentrix Enterprise (Henry Schein One) vs Practice-Web

Side-by-side from the Top 11 ranking of Best Dental Practice Management Software (2026) | Pricing & Pros Compared. Last verified June 6, 2026.

The short answer

Dentrix Enterprise (Henry Schein One) ranks higher on Top 11 (#7 vs #8) for Dentists and practice managers. Solo GPs, multi-location groups and DSOs, and specialty practices. Henry Schein's enterprise engine: one central database for unlimited sites, but heavy to implement.

At a glance

Dentrix Enterprise (Henry Schein One)Practice-Web
Top 11 rank#7 / Best Dental Practice Management Software (2026) | Pricing & Pros Compared#8 / Best Dental Practice Management Software (2026) | Pricing & Pros Compared
Score (out of 9.4)7.97.7
Best forFQHC & large enterprise dentalBudget solo & small practice
Pricing$$$ (enterprise quote only)$ ($109/mo flat, all-inclusive)
HQUnited StatesUnited States
Founded

Dentrix Enterprise (Henry Schein One)

Henry Schein's enterprise engine: one central database for unlimited sites, but heavy to implement.

www.dentrixenterprise.com/

See full entry in Best Dental Practice Management Software (2026) | Pricing & Pros Compared

Practice-Web

the highest-rated dental software at the lowest flat price. Built for the solo dentist.

practice-web.com/

See full entry in Best Dental Practice Management Software (2026) | Pricing & Pros Compared

Methodology and scoring weights live at /methodology. No vendor pays for placement — see about.